Tabriz University of Medical Sciences Depiction of Health 2008-9058 16 4 2025 11 20 Reviewers' Burnout and Challenges of Peer Review in Scientific Journals 450 455 10.34172/doh.2025.35 EN Sara Jalalzadeh https://orcid.org/0000-0001-9281-9934 Journal Article 10.34172/doh.2025.35 2025 09 20 2025 12 10 The peer review process is a key scientific indicator that differentiates scientific journals from other publications, thereby validating the research findings published within them. Today, scientific publishers are facing a dual challenge: the surge in scientific production and article submissions on the one hand, and the crisis of reviewer fatigue and burnout on the other. This trend can lead to significant challenges within the journal review system and the emergence of ethical misconduct in peer review. The crisis of reviewer burnout and the reluctance to review is considered a critical global challenge and an alarm bell for the scientific integrity and existence of journals.